Article
The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease.
Oncotarget - 10 Jan 2017
Chang Ling-Sai, Lo Mao-Hung, Li Sung-Chou, Yang Ming-Yu, Hsieh Kai-Sheng, Kuo Ho-Chang
Abstract excerpt
Previous research has found patients with the FcγRIIIB NA1 variant having increased risk of intravenous immunoglobulin (IVIG) resistance in Kawasaki disease (KD). Our previous studies revealed that elevated FcγRIIA expression correlated with the susceptibility of KD patients. We conducted this research to determine whether and how Fcγ receptors affect the susceptibility, IVIG treatment response, and coronary...
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