Article
Polymorphism of Fc gamma RIIa may affect the efficacy of gamma-globulin therapy in Kawasaki disease.
Journal of clinical immunology - 1 Jul 2005
Taniuchi Shoichiro, Masuda Midori, Teraguchi Masayuki, Ikemoto Yumiko, Komiyama Yutaka, Takahashi Hakuo, Kino Minoru, Kobayashi Yohnosuke
Abstract excerpt
We evaluated whether there is a possible relationship between the effectiveness of gamma-globulin treatment for patients with Kawasaki disease (KD) and the polymorphism of Fcgamma RIIa, IIIb, and IIIa. Genomic DNA was extracted from whole blood collected from 56 patients with KD who received gamma-globulin treatment. The genotypes for Fcgamma RIIIb-NA(1, 2), Fcgamma RIIa-H/R131, and FcgammaRIIIa-F/V158 were...
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