Article
Association of single-nucleotide polymorphisms in non-coding regions of the TLR4 gene with primary open angle glaucoma in a Mexican population.
Ophthalmic genetics - 1 Jan 2000
Navarro-Partida Jose, Alvarado Castillo Beatriz, Martinez-Rizo Abril Bernardette, Rosales-Diaz Ramses, Velazquez-Fernandez Jesus Bernardino, Santos Arturo
Abstract excerpt
BACKGROUND: Toll-like receptor 4 (TLR4) non-coding polymorphisms are associated to primary open angle glaucoma (POAG), normal tension glaucoma, and pseudoexfoliation glaucoma. This study was performed to determine whether non-coding single nucleotide polymorphisms (SNPs) in the TLR4 gene contribute to POAG in a Mexican population. MATERIAL AND METHODS: A total of 187 unrelated Mexican patients with POAG and 109...
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