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Article

Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma.

American journal of ophthalmology - 1 Nov 2012

Takano Yoshimasa, Shi Dong, Shimizu Ai, Funayama Tomoyo, Mashima Yukihiko, Yasuda Noriko, Fukuchi Takeo, Abe Haruki, Ideta Hidenao, Zheng Xiaodong, Shiraishi Atsushi, Ohashi Yuichi, Nishida Kohji, Nakazawa Toru, Fuse Nobuo

Abstract excerpt

PURPOSE: To determine whether polymorphisms in the Toll-like receptor 4 (TLR4) gene are associated with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and exfoliation glaucoma (XFG) in Japanese individuals. DESIGN: Genetic association study. METHODS: SETTING: Multicenter study. STUDY POPULATION: One hundred eighty-four unrelated Japanese patients with POAG, 365 unrelated patients with NTG,...

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Source

Identifiers

PMID: 22831837
DOI: 10.1016/j.ajo.2012.03.050

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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