Article
Lack of Association Between Polymorphism rs4986791 in TLR4 and Primary Open-Angle Glaucoma in a Saudi Cohort.
Genetic testing and molecular biomarkers - 1 Sept 2016
Mousa Ahmed, Kondkar Altaf A, Al-Obeidan Saleh A, Azad Taif A, Sultan Tahira, Osman Essam A, Abu-Amero Khaled K
Abstract excerpt
AIMS: To investigate whether single nucleotide polymorphism (SNP) rs4986791 (C>T) in the toll-like receptor 4 (TLR4) gene is a risk factor for primary open-angle glaucoma (POAG) in the Saudi population. METHOD: A case-control study was performed to genotype a cohort of 85 POAG patients and 95 matched healthy controls utilizing TaqMan(®). The association between mutant genotypes and various POAG clinical indices...
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