Article
Analysis of toll-like receptor rs4986790 polymorphism in Saudi patients with primary open angle glaucoma.
Ophthalmic genetics - 1 Jan 2000
Abu-Amero Khaled K, Kondkar Altaf A, Mousa Ahmed, Azad Taif A, Sultan Tahira, Osman Essam A, Al-Obeidan Saleh A
Abstract excerpt
BACKGROUND: To investigate whether SNP rs4986790 in toll-like receptors (TLRs) is a risk factor for primary open angle glaucoma (POAG) in a Saudi population. MATERIALS AND METHODS: A cohort of 85 unrelated POAG patients and 95 unrelated control subjects from Saudi Arabia were genotyped utilizing Taq-Man® assay. The association between mutant genotypes and various clinical indices important for POAG was...
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