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Article

Association of single-nucleotide polymorphisms in TLR4 gene and gene-environment interaction with primary open angle glaucoma in a Chinese northern population.

The journal of gene medicine - 1 Jan 2020

Liu Huijuan, Qi Shixin, He Wei, Chang Cuirong, Chen Yanhui, Yu Jianguo

Abstract excerpt

BACKGROUND: The present study aimed to investigate the association of several single nucleotide polymorphisms (SNPs) within the Toll-like receptor 4 (TLR4) gene and additional gene-environment interaction with primary open angle glaucoma (POAG) risk. METHODS: Tests for Hardy-Weinberg equilibrium in controls and haplotype analysis were performed using SNPstats (https://www.snpstats.net). Generalized multifactor...

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Identifiers

PMID: 31697008
DOI: 10.1002/jgm.3139

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