Article
Understanding the complex evolution of rapidly mutating viruses with deep sequencing: Beyond the analysis of viral diversity.
Virus research - 15 Jul 2017
Leung Preston, Eltahla Auda A, Lloyd Andrew R, Bull Rowena A, Luciani Fabio
Abstract excerpt
With the advent of affordable deep sequencing technologies, detection of low frequency variants within genetically diverse viral populations can now be achieved with unprecedented depth and efficiency. The high-resolution data provided by next generation sequencing technologies is currently recognised as the gold standard in estimation of viral diversity. In the analysis of rapidly mutating viruses, longitudinal...
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