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Advances in the pathogenesis of psoriasis: from keratinocyte perspective

24 Jan 2022

Abstract excerpt

Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration of immune cells. Here, we review the role of keratinocytes in the pathogenesis of psoriasis, focusing on factors relevant to genetics, cytokines and receptors, metabolism, cell signaling, transcription factors, non-coding RNAs,...

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PMID: 35075118
DOI: 10.1038/s41419-022-04523-3

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