Article

TCN2 promotes psoriatic skin inflammation and keratinocyte proliferation via the IL-1β-STAT3 pathway

2025-08-19

Abstract excerpt

<title>Abstract</title> <p>Psoriasis, a chronic immune-mediated inflammatory skin disorder, exerts systemic impacts across multiple organs. Although transcobalamin 2 (TCN2) has been reported to be associated with several autoimmune diseases, its role in psoriasis remains elusive. Hence, we investigated the role of TCN2 in psoriasis pathogenesis. Our results indicated that TCN2 was highly expressed in the skin tis...

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Literature Corpus work: 100fd40a-2643-510f-8a21-404857fb9711
DOI: 10.21203/rs.3.rs-7309098/v1

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