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Article

ATIC missense variant affects response to methotrexate treatment in rheumatoid arthritis patients.

Pharmacogenomics - 1 Dec 2016

Kurzawski Mateusz, Malinowski Damian, Szarmach Natalia, Nowak Anna, Goryniak Aleksandra, Pawlik Andrzej, Droździk Marek

Abstract excerpt

AIM: The study was aimed at investigation of several gene variants of folate pathway enzymes for their potential association with methotrexate (MTX) treatment response in patients with rheumatoid arthritis. PATIENTS & METHODS: Four hundred and twenty two Caucasian patients were classified as good or poor responders, and subsequently genotyped for common SNPs in DHFR, FPGS and ATIC genes. RESULTS: No significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hydroxymethyl and Formyl Transferases

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Source

Identifiers

PMID: 27885916
DOI: 10.2217/pgs-2016-0125

Genes

ATIC
DHFR
FPGS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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