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Article

Failure to launch: aberrant cumulus gene expression during oocyte in vitro maturation

22 Nov 2016

Abstract excerpt

In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal breeding, but this potential is yet to be fully realised due to reduced oocyte developmental competence in comparison with in vivo matured oocytes. Cumulus cells occupy an essential position in determining oocyte developmental competence. Here we have examined the areas of deficient gene expression, as determined...

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PMID: 27879344
DOI: 10.1530/rep-16-0426

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