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Article

Gene expression profiling of human oocytes following in vivo or in vitro maturation

17 Mar 2008

Abstract excerpt

BACKGROUND: Immature human oocytes matured in vitro, particularly those from gonadotrophin stimulated ovaries, are developmentally incompetent when compared with oocytes matured in vivo. This developmental incompetence has been explained as poor oocyte cytoplasmic maturation without any determination of the likely molecular basis of this observation. METHODS: Replicate whole human genome arrays were generated for...

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PMID: 18346995
DOI: 10.1093/humrep/den085

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