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Article

Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells.

Molecular medicine reports - 1 Dec 2016

Wang Yingge, Gao Shan, Wang Weiguang, Liang Jingyan

Abstract excerpt

Temozolomide (TMZ) is an alkylating agent used for the treatment of aggressive forms of brain tumor based on its antitumor actions. However, the exact effect on cancer and the underlying anticancer molecular mechanism of TMZ remain to be elucidated. In the present study, the effects of TMZ on the growth and motility of glioma C6 cells were investigated. MTT and Transwell assays were used to detect cellular growth...

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Source

Identifiers

PMID: 27878252
DOI: 10.3892/mmr.2016.5964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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