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Article

Epithelial‐to‐mesenchymal transition is involved in BCNU resistance in human glioma cells

22 Sept 2013

Abstract excerpt

Chemotherapy has been considered as an effective treatment for malignant glioma; however, it becomes increasingly ineffective with tumor progression. Epithelial-to-mesenchymal transition (EMT) is a process whereby cells acquire morphologic and molecular alterations that facilitate tumor metastasis and progression. Emerging evidence associates chemoresistance with the acquisition of EMT in cancer. However, it is...

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PMID: 24112388
DOI: 10.1111/neup.12062

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