Article
Clinical and genetic determinants of ovarian metastases from colorectal cancer.
Cancer - 1 Apr 2017
Ganesh Karuna, Shah Ronak H, Vakiani Efsevia, Nash Garrett M, Skottowe Hugh P, Yaeger Rona, Cercek Andrea, Lincoln Anne, Tran Christina, Segal Neil H, Reidy Diane L, Varghese Anna, Epstein Andrew S, Sonoda Yukio, Chi Dennis, Guillem Jose, Temple Larissa, Paty Philip, Hechtman Jaclyn, Shia Jinru, Weiser Martin, Aguilar Julio Garcia, Kemeny Nancy, Berger Michael F, Saltz Leonard, Stadler Zsofia K
Abstract excerpt
BACKGROUND: Ovarian metastases from colorectal cancer (OM-CRC) often are unresponsive to chemotherapy and are associated with poor survival. To the authors' knowledge, the clinicopathologic and genomic predictors of OM-CRC are poorly characterized and optimal clinical management remains unclear. METHODS: Women with a histopathological diagnosis of OM-CRC who were treated at Memorial Sloan Kettering Cancer Center...
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