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Article

Age-related common miRNA polymorphism associated with severe toxicity in lung cancer patients treated with platinum-based chemotherapy.

Clinical and experimental pharmacology & physiology - 1 Dec 2017

Fang Chao, Li Xiang-Ping, Gong Wei-Jing, Wu Na-Yiyuan, Tang Jie, Yin Ji-Ye, Li Xi, Zhang Wei, Zhou Hong-Hao, Liu Zhao-Qian

Abstract excerpt

Platinum-based chemotherapy toxicity severely impedes successful treatment in lung cancer patients. MicroRNAs (miRs) have a significant impact on the occurrence and survival rate of lung cancer. The purpose of this study was to investigate the association between common miRNA variants and platinum-based chemotherapy toxicity in lung cancer patients. A total of eight functional single nucleotide polymorphisms...

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PMID: 27873337
DOI: 10.1111/1440-1681.12704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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