Article
Association of CCND1 rs9344 polymorphism with lung cancer susceptibility and clinical outcomes: a case-control study.
BMC pulmonary medicine - 8 Apr 2024
Mei Chao, Wang Tian, Xu Baoli, Wu Sanlan, Zhang Xuelin, Lv Yongning, Zhang Yu, Liu Zhaoqian, Gong Weijing
Abstract excerpt
BACKGROUND: Cyclin D1 (CCND1) plays a pivotal role in cancer susceptibility and the platinum-based chemotherapy response. This study aims to assess the relationship between a common polymorphism (rs9344 G > A) in CCND1 gene with cancer susceptibility, platinum-based chemotherapy response, toxicities and prognosis of patients with lung cancer. METHODS: This study involved 498 lung cancer patients and 213 healthy...
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