Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lung cancer, platinum analog-based frontline treatment and pharmacogenetic limitations.

Personalized medicine - 1 Jan 2024

Saqib Maryam, Din Zari Salahud, Zafar Sehrish, Munawar Nayla, Nawaz Rukhsana, Ahmed Sagheer, Hamdard Mohammad Hamid

Abstract excerpt

Lung cancer has the highest mortality rate among all the highly prevalent neoplasia globally. The major concern with its frontline treatment-cisplatin, is the rapid progression of chemoresistance and multi-organ-based toxicities including hearing loss and tinnitus, nephrotoxicity, hepatotoxicity and myelosuppression including anemia and neutropenia. In this review, studies concluding the association of single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Multidrug Resistance-Associated Protein 2
Share to Antineoplastic Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cisplatin

Share to Drug Resistance, Neoplasm

Share to Lung Neoplasms

Share to Pharmacogenetics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39560009
DOI: 10.1080/17410541.2024.2391269

Genes

ATP7B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lung cancer, platinum analog-based frontline treatment and pharmacogenetic limitations.PMID 39560009Read ↗

Pharmacogenomics of platinum-based chemotherapy in non-small cell lung cancer: focusing on DNA repair systems.Semantic proximity Read ↗

Genetic Polymorphisms and Platinum-based Chemotherapy Treatment Outcomes in Patients with Non-Small Cell Lung Cancer: A Genetic Epidemiology Study Based Meta-analysis.Semantic proximity Read ↗

Gene-gene and gene-environment interactions influence platinum-based chemotherapy response and toxicity in non-small cell lung cancer patientsSemantic proximity Read ↗

Role of rs873601 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based ChemotherapySemantic proximity Read ↗

ATP7B rs9535826 is associated with gastrointestinal toxicity of platinum-based chemotherapy in nonsmall cell lung cancer patients.Semantic proximity Read ↗

[Single nucleotide polymorphisms in lung cancer patients and cisplatin treatment].Semantic proximity Read ↗

The ATP7B genetic polymorphisms predict clinical outcome to platinum-based chemotherapy in lung cancer patients.Semantic proximity Read ↗

Regulation of cisplatin resistance in lung cancer by epigenetic mechanismsSemantic proximity Read ↗

Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer.Semantic proximity Read ↗

Genetic Variants Associated With Response to Platinum-Based Chemotherapy in Non-Small Cell Lung Cancer Patients: A Field Synopsis and Meta-Analysis.Semantic proximity Read ↗

Genetic polymorphisms as potential pharmacogenetic biomarkers for platinum-based chemotherapy in non-small cell lung cancer.Semantic proximity Read ↗

Association between genetic polymorphisms in SLC19A1, SLCO1B1 and SLCO1B3 genes predicts survival and toxicity in North Indian lung cancer patients undergoing platinum-based doublet chemotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.