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Article

Identification of extreme motor phenotypes in Huntington's disease.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2017

Braisch Ulrike, Hay Birgit, Muche Rainer, Rothenbacher Dietrich, Landwehrmeyer G Bernhard, Long Jeffrey D, Orth Michael

Abstract excerpt

The manifestation of motor signs in Huntington's disease (HD) has a well-known inverse relationship with HTT CAG repeat length, but the prediction is far from perfect. The probability of finding disease modifiers is enhanced in individuals with extreme HD phenotypes. We aimed to identify extreme HD motor phenotypes conditional on CAG and age, such as patients with very early or very late onset of motor...

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Identifiers

PMID: 27868347
DOI: 10.1002/ajmg.b.32514

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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