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Article

Direct whole-genome sequencing of HIV-1 for clinical drug-resistance analysis and public health surveillance.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2024

Coldbeck-Shackley Rosa C, Adamson Penelope J, Whybrow Daryn, Selway Caitlin A, Papanicolas Lito E, Turra Mark, Leong Lex E X

Abstract excerpt

BACKGROUND: Human Immunodeficiency virus type 1 (HIV-1) remains a significant global health threat partly due to its ability to develop resistance to anti-retroviral therapies. HIV-1 genotype and drug resistance analysis of the polymerase (pol) sequence is a mainstay of its clinical and public health management. However, as new treatments and resistances evolve, analysis methods must change accordingly. In this...

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to pol Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 38924832
DOI: 10.1016/j.jcv.2024.105709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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