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Article

Immunological Outcomes of Antibody Binding to Glycans Shared between Microorganisms and Mammals

18 Nov 2016

Abstract excerpt

Glycans constitute basic cellular components of living organisms across biological kingdoms, and glycan-binding Abs participate in many cellular interactions during immune defense against pathogenic organisms. Glycan epitopes are expressed as carbohydrate-only entities or as oligomers or polymers on proteins and lipids. Such epitopes on glycoproteins may be formed by posttranslational modifications or neoepitopes...

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PMID: 27864551
DOI: 10.4049/jimmunol.1600872

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