Article

Autoreactive IgE: pathogenic role and therapeutic target in autoimmune diseases

2023-04-19

Abstract excerpt

Autoimmunity is the break of tolerance to self-antigens that leads to organ-specific or systemic diseases characterized by the presence of pathogenic autoreactive antibodies (AAb) produced by plasmablast and/or plasma cells. AAb are prevalent in the general population and not systematically associated with clinical symptoms. In contrast, in some individuals, these AAb are pathogenic and drive the development of si...

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Literature Corpus work: feff72ed-e096-5d04-aa8f-e5e038e5e74d
DOI: 10.22541/au.168187871.14331560/v1

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