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Article

Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review

9 Jan 2015

Abstract excerpt

Herein we will review the role of glycans in the immune system. Specific topics covered include: the glycosylation sites of IgE, IgM, IgD, IgE, IgA, and IgG; how glycans can encode "self" identity by functioning as either danger associated molecular patterns (DAMPs) or self-associated molecular patterns (SAMPs); the role of glycans as markers of protein integrity and age; how the glycocalyx can dictate the...

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PMID: 25578468
DOI: 10.1016/j.jaut.2014.12.002

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