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Article

E2F1 Orchestrates Transcriptomics and Oxidative Metabolism in Wharton's Jelly-Derived Mesenchymal Stem Cells from Growth-Restricted Infants.

PloS one - 1 Jan 2016

Tan Peck Yean, Chang Cheng Wei, Duan Kaibo, Poidinger Michael, Ng Kai Lyn, Chong Yap Seng, Gluckman Peter D, Stünkel Walter

Abstract excerpt

Wharton's jelly-derived Mesenchymal Stem Cells (MSCs) isolated from newborns with intrauterine fetal growth restriction were previously shown to exert anabolic features including insulin hypersensitivity. Here, we extend these observations and demonstrate that MSCs from small for gestational age (SGA) individuals have decreased mitochondrial oxygen consumption rates. Comparing normally grown and SGA MSCs using...

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Identifiers

PMID: 27631473
DOI: 10.1371/journal.pone.0163035
PMCID: PMC5025055

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ELOVL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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