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Article

Mechanisms of endothelial dysfunction in obstructive sleep apnea.

Vascular health and risk management - 1 Jan 2008

Atkeson Amy, Jelic Sanja

Abstract excerpt

Endothelial activation and inflammation are important mediators of accelerated atherogenesis and consequent increased cardiovascular morbidity in obstructive sleep apnea (OSA). Repetitive episodes of hypoxia/reoxygenation associated with transient cessation of breathing during sleep in OSA resemble ischemia/reperfusion injury and may be the main culprit underlying endothelial dysfunction in OSA. Additional...

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Identifiers

PMID: 19337546
DOI: 10.2147/vhrm.s4078
PMCID: PMC2663447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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