Article
Rad9a is required for spermatogonia differentiation in mice.
Oncotarget - 27 Dec 2016
Huang Lin, Wang Zhen-Bo, Qi Shu-Tao, Ma Xue-Shan, Liang Qiu-Xia, Lei Guo, Meng Tie-Gang, Liang Li-Feng, Xian Ye-Xin, Hou Yi, Sun Xiao-Fang, Zhao Yong, Wang Wei-Hua, Sun Qing-Yuan
Abstract excerpt
Spermatogenesis in testes requires precise spermatogonia differentiation. Spermatocytes lacking the Rad9a gene are arrested in pachytene prophase, implying a possible role for RAD9A in spermatogonia differentiation. However, numerous RAD9A-positive pachytene spermatocytes are still observed in mouse testes following Rad9a excision using the Stra8-Cre system, and it is unclear whether Rad9a deletion in...
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