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Mammalian gonocyte and spermatogonia differentiation: recent advances and remaining challenges

10 Feb 2015

Abstract excerpt

The production of spermatozoa relies on a pool of spermatogonial stem cells (SSCs), formed in infancy from the differentiation of their precursor cells, the gonocytes. Throughout adult life, SSCs will either self-renew or differentiate, in order to maintain a stem cell reserve while providing cells to the spermatogenic cycle. By contrast, gonocytes represent a transient and finite phase of development leading to...

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PMID: 25670871
DOI: 10.1530/rep-14-0431

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