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Article

Genomic contributors to atrial electroanatomical remodeling and atrial fibrillation progression: Pathway enrichment analysis of GWAS data.

Scientific reports - 18 Nov 2016

Husser Daniela, Ueberham Laura, Dinov Borislav, Kosiuk Jedrzej, Kornej Jelena, Hindricks Gerhard, Shoemaker M Benjamin, Roden Dan M, Bollmann Andreas, Büttner Petra

Abstract excerpt

In atrial fibrillation (AF), left atrial diameter (LAD) and low voltage area (LVA) are intermediate phenotypes that are associated with AF type and progression. In this study, we tested the hypothesis, that these phenotypes share common, genetically-determined pathways using pathway enrichment analysis of GWAS data. Samples from 660 patients with paroxysmal (n = 370) or persistent AF (n = 290) were genotyped for...

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PMID: 27857207
DOI: 10.1038/srep36630
PMCID: PMC5114680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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