Article

Discrete mechanistic pathways underlying genetic predisposition to atrial fibrillation are associated with different intermediate cardiac phenotypes and risk of cardioembolic stroke

2024-07-16

Abstract excerpt

<h4>Background: </h4> Genome-wide association studies (GWAS) have clustered candidate genes associated with atrial fibrillation (AF) into biological pathways reflecting different pathophysiological mechanisms. We investigated whether these pathways associate with distinct intermediate phenotypes and confer differing risks of cardioembolic stroke. Methods Three distinct subsets of AF-associated genetic variants, ea...

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Literature Corpus work: d6166f27-9a3d-5917-9096-703d5165dba8
DOI: 10.1101/2024.07.10.24310244

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