Article
N-Linked glycans are an important component of the processive machinery of cellobiohydrolases.
Biochimie - 1 Jan 2017
Gusakov Alexander V, Dotsenko Anna S, Rozhkova Aleksandra M, Sinitsyn Arkady P
Abstract excerpt
Cellobiohydrolases (CBHs), belonging to glycoside hydrolase families 6 and 7 (GH6 and GH7), are the major components of cellulase systems of filamentous fungi involved in biodegradation of cellulose in nature. Previous studies demonstrated that N-linked glycans in the catalytic domains of GH7 CBHs significantly affect the enzyme activity against cellulosic substrates. The influence of N-linked glycans on the...
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