Article
In Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin.
Antimicrobial agents and chemotherapy - 1 Feb 2017
Singh Madhuri, Matsuo Miki, Sasaki Takashi, Morimoto Yuh, Hishinuma Tomomi, Hiramatsu Keiichi
Abstract excerpt
The mechanisms underlying bacterial tolerance to antibiotics are unclear. A possible adaptation strategy was explored by exposure of drug-naive methicillin-susceptible Staphylococcus aureus strain FDA209P to vancomycin in vitro Strains surviving vancomycin treatment (vancomycin survivor strains), which appeared after 96 h of exposure, were slow-growing derivatives of the parent strain. Although the vancomycin...
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