Article
The evolution of vancomycin intermediate Staphylococcus aureus (VISA) and heterogenous-VISA.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2014
Howden Benjamin P, Peleg Anton Y, Stinear Timothy P
Abstract excerpt
Resistance to new antimicrobials is generally recognized in Staphylococcus aureus soon after they are released for clinical use. In the case of vancomycin, which was first released in the 1950s, resistance was not reported until the mid 1990s, with the description of vancomycin-intermediate S. aureus (VISA), and heterogenous-VISA (hVISA). Unraveling the complex genetic and cell wall structural changes conferring...
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