Article
Association between GWAS-Derived rs966423 Genetic Variant and Overall Mortality in Patients with Differentiated Thyroid Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2016
Świerniak Michał, Wójcicka Anna, Czetwertyńska Małgorzata, Długosińska Joanna, Stachlewska Elżbieta, Gierlikowski Wojciech, Kot Adam, Górnicka Barbara, Koperski Łukasz, Bogdańska Magdalena, Wiechno Wiesław, Jażdżewski Krystian
Abstract excerpt
PURPOSE: Five germline genetic variants (rs116909374, rs965513, rs944289, rs966423, and rs2439302) have been associated in genome-wide association studies (GWAS) with increased risk of differentiated thyroid cancer (DTC), but their role in mortality of patients has not been established. Also, no preoperative marker of the clinical outcome of thyroid cancer had yet been identified. The aim of the study was to...
