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Article

Lack of Associations between XPC Gene Polymorphisms and Neuroblastoma Susceptibility in a Chinese Population.

BioMed research international - 1 Jan 2016

Zheng Jintao, Zhang Ruizhong, Zhu Jinhong, Wang Fenghua, Yang Tianyou, He Jing, Xia Huimin

Abstract excerpt

Neuroblastoma is one of the most malignant solid tumors in infants and young children. No more than 40% of neuroblastoma patients can survive for longer than five years after it has been diagnosed. XPC protein is a pivotal factor that recognizes DNA damage and starts up the nucleotide excision repair (NER) in mammalian cells. This makes up the first group to defend against the cancer. Previous studies have...

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Identifiers

PMID: 27847809
DOI: 10.1155/2016/2932049
PMCID: PMC5101359

Genes

XPC

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