Article
Functional Polymorphisms at ERCC1/XPF Genes Confer Neuroblastoma Risk in Chinese Children.
EBioMedicine - 1 Apr 2018
Zhuo Zhen-Jian, Liu Wei, Zhang Jiao, Zhu Jinhong, Zhang Ruizhong, Tang Jue, Yang Tianyou, Zou Yan, He Jing, Xia Huimin
Abstract excerpt
Variations in nucleotide excision repair pathway genes may predispose to initiation of cancers. However, polymorphisms of ERCC1/XPF genes and neuroblastoma risk have not been investigated before. To evaluate the relevance of polymorphisms of ERCC1/XPF genes in influencing neuroblastoma susceptibility, we genotyped four polymorphisms in ERCC1/XPF genes using a Chinese population of 393 cases and 812 controls. The...
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