Association between GPC2 polymorphisms and neuroblastoma risk in Chinese children.

doi:10.1002/jcla.24866

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Article

Association between GPC2 polymorphisms and neuroblastoma risk in Chinese children.

Journal of clinical laboratory analysis - 1 Mar 2023

Li Meng, Zhang Xinxin, Liu Jiabin, Zhou Chunlei, Miao Lei, He Jing, Wu Haiyan, Zhang Ruizhong

Abstract excerpt

BACKGROUND: The cell surface glycoprotein glypican 2 (GPC2) has been shown to increase susceptibility to neuroblastoma, which is the most common malignancy in children. However, associations between single nucleotide polymorphism(s) of GPC2 and neuroblastoma risk remain unclarified. METHODS: We conducted a case-control study to investigate two GPC2 polymorphisms (rs1918353 G>A and rs7799441 C>T) in 473 healthy...

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PMID: 36920409
DOI: 10.1002/jcla.24866
PMCID: PMC10098060

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