Article
Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin.
PloS one - 1 Jan 2016
Galesloot Tessel E, Verweij Niek, Traglia Michela, Barbieri Caterina, van Dijk Freerk, Geurts-Moespot Anneke J, Girelli Domenico, Kiemeney Lambertus A L M, Sweep Fred C G J, Swertz Morris A, van der Meer Peter, Camaschella Clara, Toniolo Daniela, Vermeulen Sita H, van der Harst Pim, Swinkels Dorine W
Abstract excerpt
Serum hepcidin concentration is regulated by iron status, inflammation, erythropoiesis and numerous other factors, but underlying processes are incompletely understood. We studied the association of common and rare single nucleotide variants (SNVs) with serum hepcidin in one Italian study and two large Dutch population-based studies. We genotyped common SNVs with genome-wide association study (GWAS) arrays and...
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