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Article

Reciprocal Translocation Carrier Diagnosis in Preimplantation Human Embryos.

EBioMedicine - 1 Dec 2016

Hu Liang, Cheng Dehua, Gong Fei, Lu Changfu, Tan Yueqiu, Luo Keli, Wu Xianhong, He Wenbing, Xie Pingyuan, Feng Tao, Yang Kai, Lu Guangxiu, Lin Ge

Abstract excerpt

Preimplantation genetic diagnosis (PGD) is widely applied in reciprocal translocation carriers to increase the chance for a successful live birth. However, reciprocal translocation carrier embryos were seldom discriminated from the normal ones mainly due to the technique restriction. Here we established a clinical applicable approach to identify precise breakpoint of reciprocal translocation and to further...

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Source

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Identifiers

PMID: 27840008
DOI: 10.1016/j.ebiom.2016.11.007
PMCID: PMC5161423

Genes

PGD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Successful pregnancy to a complex chromosome rearrangement carrier by next-generation cytogenetics and preimplantation genetic testingSemantic proximity Read ↗

Distinguishing between carrier and noncarrier embryos with the use of long-read sequencing in preimplantation genetic testing for reciprocal translocationsSemantic proximity Read ↗

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Clinical application of next-generation sequencing in preimplantation genetic diagnosis cycles for Robertsonian and reciprocal translocationsSemantic proximity Read ↗

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Validation of Next-Generation Sequencing and Array Comparative Genomic Hybridization for Diagnosis and Screening of Reciprocal and Robertsonian Translocations in Human BlastocystsSemantic proximity Read ↗

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