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Article

Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease.

Clinical epigenetics - 1 Jan 2017

Nakatochi Masahiro, Ichihara Sahoko, Yamamoto Ken, Naruse Keiko, Yokota Shigeki, Asano Hiroyuki, Matsubara Tatsuaki, Yokota Mitsuhiro

Abstract excerpt

BACKGROUND: Development of cardiovascular disease (CVD), including coronary artery disease, arrhythmia, and ischemic stroke, depends on environmental and genetic factors. To investigate the epigenetic basis of myocardial infarction (MI), we performed an epigenome-wide association study for this condition in elderly Japanese subjects. A total of 192 case subjects with MI and 192 control subjects were recruited...

Topics

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Cross-Sectional Studies
DNA Helicases
DNA Methylation
Epigenesis, Genetic
Epigenomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homeodomain Proteins

Myocardial Infarction

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Open in PubMed Open full text

Identifiers

PMID: 28515798
DOI: 10.1186/s13148-017-0353-3
PMCID: PMC5432989

Genes

SMARCA4
ZFHX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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