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Article

Site-Directed Mutagenesis and Its Application in Studying the Interactions of T3S Components.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Francis Matthew S, Amer Ayad A A, Milton Debra L, Costa Tiago R D

Abstract excerpt

Type III secretion systems are a prolific virulence determinant among Gram-negative bacteria. They are used to paralyze the host cell, which enables bacterial pathogens to establish often fatal infections-unless an effective therapeutic intervention is available. However, as a result of a catastrophic rise in infectious bacteria resistant to conventional antibiotics, these bacteria are again a leading cause of...

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PMID: 27837478
DOI: 10.1007/978-1-4939-6649-3_2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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