Article
Erythropoietin and co.: intrinsic structure and functional disorder.
Molecular bioSystems - 20 Dec 2016
Uversky Vladimir N, Redwan Elrashdy M
Abstract excerpt
Erythropoietin (Epo) is a heavily glycosylated protein, with its main function being related to erythropoiesis, where it controls red blood cell production via interaction with the Epo receptor (EpoR). It also plays a number of important roles in various hormonal, growth factor, and cytokine pathways. These roles are defined by Epo partners, such as the homodimeric (EpoR)2 receptor, the heterodimeric EpoR/βCR...
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