Article
Congenital erythrocytosis.
European journal of haematology - 1 Jul 2021
Mallik Nabhajit, Das Reena, Malhotra Pankaj, Sharma Prashant
Abstract excerpt
Erythrocytosis, or increased red cell mass, may be labeled as primary or secondary, depending on whether the molecular defect is intrinsic to the red blood cells/their precursors or extrinsic to them, the latter being typically associated with elevated erythropoietin (EPO) levels. Inherited/congenital erythrocytosis (CE) of both primary and secondary types is increasingly recognized as the cause in many patients...
Topics
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Bisphosphoglycerate Mutase
- Erythrocytes
- Erythropoietin
- Hemoglobins
- Humans
- Hypoxia-Inducible Factor-Proline Dioxygenases
- Mice
- Mutation
- Oxygen