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Article

Oxygen sensing: recent insights from idiopathic erythrocytosis.

Cell cycle (Georgetown, Tex.) - 1 May 2006

Lee Frank S, Percy Melanie J, McMullin Mary Frances

Abstract excerpt

Idiopathic erythrocytosis (IE) is a rare condition in which there is an increase in red cell mass and hematocrit. As it is typically driven by elevated or inappropriately normal erythropoietin (Epo) levels, it has the potential to reveal the identities of proteins involved in the oxygen sensing pathway that regulates the transcription factor, Hypoxia Inducible Factor (HIF), and hence Epo production in humans. One...

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Identifiers

PMID: 16687917
DOI: 10.4161/cc.5.9.2723
PMCID: PMC2422869

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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