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Article

Allele-specific splicing effects on DKKL1 and ZNF419 transcripts in HeLa cells.

Gene - 20 Jan 2017

Martin Grace, Selcuklu S Duygu, Schouest Katherine, Nembaware Victoria, McKeown Peter C, Seoighe Cathal, Spillane Charles

Abstract excerpt

Allele-specific splicing is the production of different RNA isoforms from different alleles of a gene. Altered splicing patterns such as exon skipping can have a dramatic effect on the final protein product yet have traditionally proven difficult to predict. We investigated the splicing effects of a set of nine single nucleotide polymorphisms (SNPs) which are predicted to have a direct impact on mRNA splicing,...

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Source

Identifiers

PMID: 27826023
DOI: 10.1016/j.gene.2016.11.004

Genes

DKKL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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