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Article

Saliva initiates the formation of pro-inflammatory macrophages in vitro.

Archives of oral biology - 1 Jan 2017

Pourgonabadi Solmaz, Müller Heinz-Dieter, Mendes João Rui, Gruber Reinhard

Abstract excerpt

OBJECTIVES: Saliva can support oral wound healing, a process that requires a temporary inflammatory reaction. We have reported previously that saliva provokes a strong inflammatory response in oral fibroblasts. Bone marrow cells also give rise to macrophages, a heterogeneous subset of cell population involved in wound healing. Lipopolysaccharide (LPS) and interleukin 4 (IL-4) induce activation of pro-(M1), and...

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PMID: 27825074
DOI: 10.1016/j.archoralbio.2016.10.012

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TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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