Article
Role of salivary epithelial toll-like receptors 2 and 4 in modulating innate immune responses in chronic periodontitis.
Journal of periodontal research - 1 Dec 2013
Swaminathan V, Prakasam S, Puri V, Srinivasan M
Abstract excerpt
BACKGROUND AND OBJECTIVE: Chronic periodontitis is initiated by sequential colonization with a broad array of bacteria and is perpetuated by an immune-inflammatory response to the changing biofilm. Host recognition of microbes is largely mediated by toll-like receptors (TLRs), which interact with conserved pathogen-associated molecular patterns. Based on ligand recognition, TLR-2 and TLR-4 interact with most...
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