Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipopolysaccharide induces the migration of human dental pulp cells by up-regulating miR-146a.

Journal of endodontics - 1 Dec 2012

Wang Min-Ching, Hung Pei-Shih, Tu Hsi-Feng, Shih Wen-Yu, Li Wan-Chun, Chang Kuo-Wei

Abstract excerpt

INTRODUCTION: MicroRNAs are small noncoding RNAs that play crucial roles in regulating normal and pathologic functions. Bacterial lipopolysaccharide (LPS) is one of the key regulators of pulpal pathogenesis. This study investigated how LPS regulates microRNA expression and affects the phenotype of human dental pulp cells (DPCs). METHODS: Primary DPCs were established and immortalized to achieve immortalized DPCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Culture Techniques
Share to Dental Pulp

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Gene Silencing

Share to Interleukin-1 Receptor-Associated Kinases

Share to Lipopolysaccharides

Share to Osteogenesis

Share to TNF Receptor-Associated Factor 6

Source

Identifiers

PMID: 23146644
DOI: 10.1016/j.joen.2012.09.008

Genes

IRAK1
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipopolysaccharide induces the migration of human dental pulp cells by up-regulating miR-146a.PMID 23146644Read ↗

MicroRNA-27a-5p downregulates the expression of proinflammatory cytokines in lipopolysaccharide-stimulated human dental pulp cells via NF-κB signaling pathwaySemantic proximity Read ↗

miR-140-5p-mediated regulation of the proliferation and differentiation of human dental pulp stem cells occurs through the lipopolysaccharide/toll-like receptor 4 signaling pathway.Semantic proximity Read ↗

MiR-146b protects against pediatric pneumonia progression through MyD88/NF-κB signaling pathwaySemantic proximity Read ↗

Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profileSemantic proximity Read ↗

Dysregulation of MicroRNA-455-5p Contributes to Pulpitis Pathogenesis Through Modulating MYD88Semantic proximity Read ↗

Evaluating the effect of LPS from periodontal pathogenic bacteria on the expression of senescence‐related genes in human dental pulp stem cellsSemantic proximity Read ↗

A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells.Semantic proximity Read ↗

Effects of sclerostin on lipopolysaccharide-induced inflammatory phenotype in human odontoblasts and dental pulp cells.Semantic proximity Read ↗

Stathmin regulates the proliferation and differentiation of inflammatory hDPSCs through canonical Wnt/β-catenin pathwaySemantic proximity Read ↗

Effects of miR-629-5p on odontoblast differentiation and target gene TEAD4 expression of dental pulp stem cellsSemantic proximity Read ↗

Exosomes From LPS-stimulated hDPSCs Promote the Angiogenesis of HUVECsSemantic proximity Read ↗

Signal regulatory protein α associated with the progression of oral leukoplakia and oral squamous cell carcinoma regulates phenotype switch of macrophages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.