Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro-Inflammatory Bias.

Abstract excerpt

AIM: Understanding macrophage polarization in periodontitis is critical for elucidating the underlying disease mechanisms. This exploratory study aimed to characterize phenotypic features of monocyte-derived macrophages (MDMs) from treated periodontitis patients. METHODS: Peripheral blood mononuclear cells were isolated from 30 individuals classified into three groups: periodontal healthy (H) and patients with...

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