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Article

Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis

7 Nov 2016

Abstract excerpt

ANCA-associated vasculitis is an autoimmune condition characterized by vascular inflammation and organ damage. Pharmacologically induced remission of this condition is complicated by relapses. Potential triggers of relapse are immunologic challenges and environmental insults, both of which associate with changes in epigenetic silencing modifications. Altered histone modifications implicated in gene silencing...

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Identifiers

PMID: 27821628
DOI: 10.1681/asn.2016050548

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